FORMULATION AND CHARACTERIZATION OF ZEAXANTHIN NANOEMULSION RADIANCE SERUM AS ANTIOXIDANT

Objective: This study aimed to increase the effectiveness of using zeaxanthin by developed nanoemulsion containing which was then formulated into radiance serum for topical use.
 Methods: Nanoemulsions are made spontaneous nano emulsification methods/techniques, relatively simple technologically because they rely on right combination selected surfactants and co-surfactants. The optimization formula carried out starting from determining oil: surfactant: co-surfactant phase ratio concentration zeaxanthin. Nanoemulsion characterization in form physical includes organoleptic tests, globule size polydispersity index, zeta potential, pH entrapment efficiency tests. best results were combined preparations tested evaluation preparations, including organoleptic, homogeneity, viscosity, pH, spreadability, antioxidant test.
 Results: showed that had a range 20-24 nm (with normal distribution curve), index value less than 0.3, potential greater (-20) mV ranging 80-85%.
 Conclusion: good physical, chemical stability properties during storage with an IC50 50 ppm.